Gene Expression/Drug Resistance
Professor of Pathology & Molecular Medicine, Oncology & Biomedical & Molecular Sciences
Department of Biomedical and Molecular Sciences
Cancer Research Institute, Ste. 300
10 Stuart Street (behind Botterell Hall)
T (613) 533-6626
F (613) 533-6830
Our research involves a comprehensive range of studies of the structure, mechanism of action, regulation of expression and subcellular trafficking of several members of the ATP Binding Cassette (ABC) superfamily of transmembrane transporters. We are particularly interested in the Multidrug Resistance Protein (MRP) subfamily of ABC transporters, specifically, ABCC/MRP1, 2 and 3, and another member of the superfamily, ABCA1. Read more...